The founder, Hayashizaki Jinsuke Minamotono Shigenobu, lived in Oushu (currently Miyagi, Aomori, Fukushima and part of Akita prefecture) during the Ashikaga period. He sought revenge in the name of his father and he prayed at the Hayashizaki Myojin shrine for this outcome. He trained hard and his final enlightenment was discovering the miraculous nature of Iai Jutsu. This style became known as the Shigenobu style. Since then, multiple lines have evolved.
This evolution was especially prominent in the 7th generation, when Hasegawa Mondonosuke Eishin added creativity to the existing heritage style. The Hasegawa Mondonosuke Eishin infusion, his technique, was so miraculous that it was renamed Hasegawa Eishin Ryu, later recognized as Muso Jikiden Eishin Ryu.
In 1674 - Enpou 2, the 9th generation, Hayashi Roku Dayu Yasumasa served the Tosa Domain and established his style, Eishin Ryu. Since then, the Tosa Domain guarded his techniques as house secrets and passed the knowledge on to succeeding generations. The 17th generation, Ooe Masamichikei, was concerned that Budo would decline and decided to open the gate and disseminate the techniques widely. The 18th generation, Yamauchi Toyotake, who was related to the Tosa Domain, published Iai Shousetsu. The 19th generation, Kono Kanemitsu, founded Meibukan in Toshima-ku, Tokyo. The 20th generation, Onoe Masamitsu, inherited the cumulative knowledge of Muso Jikiden Eishin Ryu Iai Jutsu and passed it to the 21st generation, Sekiguchi Komei.